今回は【産前ケアってなに?】という疑問から生まれる、様々な疑問に対して科学的に調べました。
産前ケアとはなにか?を調べるにあたって1番最初に感じた疑問は「産前ケアってなんのためにするの?」ということです。
それを調べる中で生まれた疑問は以下のようなものです。
以下の疑問に対して科学的に正確に答えられない人、気になる人の参考になる講座になります。
今回の講座はどんな業態、業種の人でも(鍼灸師、整体師、助産師、理学療法士、インストラクター、その他)受けられるように設計しています。
*この講座はオンラインのみです。
*産前ケアとは何かを考える講座で、手技について詳しくお伝えする講座ではありません。
産前ケア
- 産前ケアの意義とは?
- 産前ケア事業の目的とは?
- 安産とは?
- 安産になるためには何をするべき?
- 胎児の姿勢が正常(屈位/前方後頭位)にならないとはどうして?
- 安産にならない要因とは?
- 切迫早産が起きる理由は?
- お腹が張るメカニズム(子宮収縮のメカニズム)とは?
- 妊娠中の不調のメカニズムとは?
- 骨盤ケアの意義とは?
- 一般の骨盤ケアとの違いとは?
- 産前ケアと骨盤ケアの違いとは?
骨盤のゆがみ
- 骨盤のゆがみとは?
- 一般、産前、産後のゆがみの定義の違いとは?
- 産前のゆがみで起こりうるトラブルとは?
- リラキシンと早産の関係とは?
- 骨盤ケアの手段とは?
まとめ
- 産前ケアでするべきことは?
- 産前ケアの手段 / 方法
講座のエビデンス
参考書籍
- 児頭回旋を極める: WEB動画でよくわかる 回旋異常のメカニズムとその対応
https://amzn.to/4aR5rte - 産後リハにおける腹部・骨盤へのアプローチ―腟・会陰部のケア,尿失禁,骨盤臓器脱,会陰・骨盤痛の予防のためのエクササイズ
https://amzn.to/3JyDqL3 - ペリネイタルケア 2023年3月号 <特集>分娩時から始める骨盤底(ぺリネ)ケア(第42巻3号)
https://amzn.to/3UvxoBk - これからの切迫早産管理 長期安静・持続点滴はやめよう
https://amzn.to/3Uy3Ym8 - 助産雑誌 2007年 03月号 [雑誌]
https://amzn.to/49XFBma - 体幹と骨盤の評価と運動療法 改訂版
https://amzn.to/3UwxyIq - 目醒める! 大腰筋 コアを鍛えて内面から身心を改善
https://amzn.to/3UwToLV - 骨盤と仙腸関節の機能解剖―骨盤帯を整えるリアラインアプローチ
https://amzn.to/49X31rM
参考文献
目次
産前ケア
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- Mens JM. Does a pelvic belt reduce hip adduction weakness in pregnancy-related posterior pelvic girdle pain? A case-control study. Eur J Phys Rehabil Med. 2017 Aug;53(4):575-581. doi: 10.23736/S1973-9087.17.04442-2. Epub 2017 Mar 1. PMID: 28251846.
- Ramírez SI. Prenatal Care: An Evidence-Based Approach. Am Fam Physician. 2023 Aug;108(2):139-150. PMID: 37590852.
- Komisaruk BR, Sansone G. Neural pathways mediating vaginal function: the vagus nerves and spinal cord oxytocin. Scand J Psychol. 2003 Jul;44(3):241-50. doi: 10.1111/1467-9450.00341. PMID: 12914587.
- 中村幸代, 堀内成子, and 柳井晴夫. "妊婦の冷え症と微弱陣痛・遷延分娩との因果効果の推定—傾向スコアによる交絡因子の調整—." 日本看護科学会誌 33.4 (2013): 4_3-4_12.
- Davenport MH, Nagpal TS, Mottola MF, Skow RJ, Riske L, Poitras VJ, Jaramillo Garcia A, Gray CE, Barrowman N, Meah VL, Sobierajski F, James M, Nuspl M, Weeks A, Marchand AA, Slater LG, Adamo KB, Davies GA, Barakat R, Ruchat SM. Prenatal exercise (including but not limited to pelvic floor muscle training) and urinary incontinence during and following pregnancy: a systematic review and meta-analysis. Br J Sports Med. 2018 Nov;52(21):1397-1404. doi: 10.1136/bjsports-2018-099780. Erratum in: Br J Sports Med. 2019 Jan;53(2):e1. Erratum in: Br J Sports Med. 2020 Mar;54(5):e3. PMID: 30337466.
- Phelan ST. Components and timing of prenatal care. Obstet Gynecol Clin North Am. 2008 Sep;35(3):339-53, vii. doi: 10.1016/j.ogc.2008.06.002. PMID: 18760223.
- Moos MK. Prenatal care: limitations and opportunities. J Obstet Gynecol Neonatal Nurs. 2006 Mar-Apr;35(2):278-85. doi: 10.1111/j.1552-6909.2006.00039.x. PMID: 16620256.
産後の骨盤
- Parker EA, Meyer AM, Goetz JE, Willey MC, Westermann RW. Do Relaxin Levels Impact Hip Injury Incidence in Women? A Scoping Review. Front Endocrinol (Lausanne). 2022 Feb 4;13:827512. doi: 10.3389/fendo.2022.827512. PMID: 35185802; PMCID: PMC8855110.
- Daneau C, Houle M, Pasquier M, Ruchat SM, Descarreaux M. Association Between Pregnancy-Related Hormones and Lumbopelvic Pain Characteristics in Pregnant Women: A Scoping Review. J Manipulative Physiol Ther. 2021 Sep;44(7):573-583. doi: 10.1016/j.jmpt.2021.10.001. Epub 2021 Dec 9. PMID: 34895733.
- Daneau C, Abboud J, Marchand AA, Houle M, Pasquier M, Ruchat SM, Descarreaux M. Mechanisms Underlying Lumbopelvic Pain During Pregnancy: A Proposed Model. Front Pain Res (Lausanne). 2021 Dec 2;2:773988. doi: 10.3389/fpain.2021.773988. PMID: 35295430; PMCID: PMC8915559.
- Capobianco R, Cher D; SIFI Study Group. Safety and effectiveness of minimally invasive sacroiliac joint fusion in women with persistent post-partum posterior pelvic girdle pain: 12-month outcomes from a prospective, multi-center trial. Springerplus. 2015 Oct 5;4:570. doi: 10.1186/s40064-015-1359-y. PMID: 26543705; PMCID: PMC4627991.
- Wuytack F, Begley C, Daly D. Risk factors for pregnancy-related pelvic girdle pain: a scoping review. BMC Pregnancy Childbirth. 2020 Nov 27;20(1):739. doi: 10.1186/s12884-020-03442-5. PMID: 33246422; PMCID: PMC7694360.
- Wiezer M, Hage-Fransen MAH, Otto A, Wieffer-Platvoet MS, Slotman MH, Nijhuis-van der Sanden MWG, Pool-Goudzwaard AL. Risk factors for pelvic girdle pain postpartum and pregnancy related low back pain postpartum; a systematic review and meta-analysis. Musculoskelet Sci Pract. 2020 Aug;48:102154. doi: 10.1016/j.msksp.2020.102154. Epub 2020 May 5. PMID: 32560862.
- Hage-Fransen MAH, Wiezer M, Otto A, Wieffer-Platvoet MS, Slotman MH, Nijhuis-van der Sanden MWG, Pool-Goudzwaard AL. Pregnancy- and obstetric-related risk factors for urinary incontinence, fecal incontinence, or pelvic organ prolapse later in life: A systematic review and meta-analysis. Acta Obstet Gynecol Scand. 2021 Mar;100(3):373-382. doi: 10.1111/aogs.14027. Epub 2020 Nov 2. PMID: 33064839.
- Dunn G, Egger MJ, Shaw JM, Yang J, Bardsley T, Powers E, Nygaard IE. Trajectories of lower back, upper back, and pelvic girdle pain during pregnancy and early postpartum in primiparous women. Womens Health (Lond). 2019 Jan-Dec;15:1745506519842757. doi: 10.1177/1745506519842757. PMID: 30991911; PMCID: PMC6472169.
- Bjelland EK, Eberhard-Gran M, Nielsen CS, Eskild A. Age at menarche and pelvic girdle syndrome in pregnancy: a population study of 74 973 women. BJOG. 2011 Dec;118(13):1646-52. doi: 10.1111/j.1471-0528.2011.03099.x. Epub 2011 Sep 6. PMID: 21895953.
- Shiri R, Coggon D, Falah-Hassani K. Exercise for the prevention of low back and pelvic girdle pain in pregnancy: A meta-analysis of randomized controlled trials. Eur J Pain. 2018 Jan;22(1):19-27. doi: 10.1002/ejp.1096. Epub 2017 Sep 4. PMID: 28869318.
- 赤尾静香, et al. "産後女性における骨盤痛と骨盤アライメントの関連性." 理学療法学 Supplement Vol. 42 Suppl. No. 2 (第 50 回日本理学療法学術大会 抄録集). 日本理学療法士協会 (現 一般社団法人日本理学療法学会連合), 2015.
リラキシン
- Kobayashi M, Sekine H, Ogawa Y, Toyama S, Komukai Y, Nakamura M, Mitanda R, Hayashi M, Kobayashi M, Hori T. Relaxin contributes to the elevation of monocytic myeloid-derived suppressor cells in peripheral blood of pregnant canines. J Reprod Immunol. 2023 Feb;155:103778. doi: 10.1016/j.jri.2022.103778. Epub 2022 Nov 26. PMID: 36455400.
- Goldsmith LT, Weiss G, Steinetz BG. Relaxin and its role in pregnancy. Endocrinol Metab Clin North Am. 1995 Mar;24(1):171-86. PMID: 7781625.
- Vrachnis N, Grigoriadis C, Siristatidis C, Vlachadis N, Balakitsas N, Mastorakos G, Iliodromiti Z. The Janus face of maternal serum relaxin: a facilitator of birth, might it also induce preterm birth? J Matern Fetal Neonatal Med. 2015;28(18):2187-91. doi: 10.3109/14767058.2014.981804. Epub 2014 Nov 18. PMID: 25363010.
- Petersen LK, Hvidman L, Uldbjerg N. Normal serum relaxin in women with disabling pelvic pain during pregnancy. Gynecol Obstet Invest. 1994;38(1):21-3. doi: 10.1159/000292438. PMID: 7959320.
- Aldabe D, Ribeiro DC, Milosavljevic S, Dawn Bussey M. Pregnancy-related pelvic girdle pain and its relationship with relaxin levels during pregnancy: a systematic review. Eur Spine J. 2012 Sep;21(9):1769-76. doi: 10.1007/s00586-012-2162-x. Epub 2012 Feb 4. PMID: 22310881; PMCID: PMC3459115.
- Albert H, Godskesen M, Westergaard JG, Chard T, Gunn L. Circulating levels of relaxin are normal in pregnant women with pelvic pain. Eur J Obstet Gynecol Reprod Biol. 1997 Jul;74(1):19-22. doi: 10.1016/s0301-2115(97)00076-6. PMID: 9243195.
- Hansen A, Jensen DV, Larsen E, Wilken-Jensen C, Petersen LK. Relaxin is not related to symptom-giving pelvic girdle relaxation in pregnant women. Acta Obstet Gynecol Scand. 1996 Mar;75(3):245-9. doi: 10.3109/00016349609047095. PMID: 8607337.
- MacLennan AH. The role of the hormone relaxin in human reproduction and pelvic girdle relaxation. Scand J Rheumatol Suppl. 1991;88:7-15. PMID: 2011710.
- Vøllestad NK, Torjesen PA, Robinson HS. Association between the serum levels of relaxin and responses to the active straight leg raise test in pregnancy. Man Ther. 2012 Jun;17(3):225-30. doi: 10.1016/j.math.2012.01.003. Epub 2012 Jan 30. PMID: 22284767.
- Weiss G, Goldsmith LT, Sachdev R, Von Hagen S, Lederer K. Elevated first-trimester serum relaxin concentrations in pregnant women following ovarian stimulation predict prematurity risk and preterm delivery. Obstet Gynecol. 1993 Nov;82(5):821-8. PMID: 8414331.
- 第一生理, et al. "レラキシンと子宮筋弛緩." J. Smooth Muscle Res 27 (1991): 67-74.
- Goldsmith LT, Weiss G. Relaxin in human pregnancy. Ann N Y Acad Sci. 2009 Apr;1160:130-5. doi: 10.1111/j.1749-6632.2008.03800.x. PMID: 19416173; PMCID: PMC3856209.
- Bryant-Greenwood GD, Yamamoto SY, Lowndes KM, Webster LE, Parg SS, Amano A, Bullesbach EE, Schwabe C, Millar LK. Human decidual relaxin and preterm birth. Ann N Y Acad Sci. 2005 May;1041:338-44. doi: 10.1196/annals.1282.054. PMID: 15956731.
- Bain E, Heatley E, Hsu K, Crowther CA. Relaxin for preventing preterm birth. Cochrane Database Syst Rev. 2013 Aug 16;(8):CD010073. doi: 10.1002/14651858.CD010073.pub2. PMID: 23949874.
- Sherwood OD. Relaxin's physiological roles and other diverse actions. Endocr Rev. 2004 Apr;25(2):205-34. doi: 10.1210/er.2003-0013. PMID: 15082520.
- Challis JRG, Matthews SG, Gibb W, Lye SJ. Endocrine and paracrine regulation of birth at term and preterm. Endocr Rev. 2000 Oct;21(5):514-50. doi: 10.1210/edrv.21.5.0407. PMID: 11041447.
- Pachuliya, O., Bespalova, O., Butenko, M., Milyutina, Y., Tral, T., & Tolibova, G. (2021). “Relaxin-dependent” way of implementing spontaneous preterm labor in multiple pregnancies: The involvement of placental relaxin 2. Journal of obstetrics and women's diseases. https://doi.org/10.17816/jowd60946.
- Vrachnis N, Grigoriadis C, Siristatidis C, Vlachadis N, Balakitsas N, Mastorakos G, Iliodromiti Z. The Janus face of maternal serum relaxin: a facilitator of birth, might it also induce preterm birth? J Matern Fetal Neonatal Med. 2015;28(18):2187-91. doi: 10.3109/14767058.2014.981804. Epub 2014 Nov 18. PMID: 25363010.
- Garibay-Tupas JL, Okazaki KJ, Tashima LS, Yamamoto S, Bryant-Greenwood GD. Regulation of the human relaxin genes H1 and H2 by steroid hormones. Mol Cell Endocrinol. 2004 Apr 30;219(1-2):115-25. doi: 10.1016/j.mce.2004.01.004. PMID: 15149733.
- Winkler M, Rath W. Zur Rolle von Zytokinen bei Weheninduktion, Zervixreifung und Blasensprung [The role of cytokines in the induction of labor, cervical ripening and rupture of the fetal membranes]. Z Geburtshilfe Neonatol. 1996;200 Suppl 1:1-12. German. PMID: 16764118.
- Masini E, Nistri S, Vannacci A, Bani Sacchi T, Novelli A, Bani D. Relaxin inhibits the activation of human neutrophils: involvement of the nitric oxide pathway. Endocrinology. 2004 Mar;145(3):1106-12. doi: 10.1210/en.2003-0833. Epub 2003 Nov 20. PMID: 14630720.
- Bryant-Greenwood GD, Yamamoto SY, Sadowsky DW, Gravett MG, Novy MJ. Relaxin stimulates interleukin-6 and interleukin-8 secretion from the extraplacental chorionic cytotrophoblast. Placenta. 2009 Jul;30(7):599-606. doi: 10.1016/j.placenta.2009.04.009. Epub 2009 May 20. PMID: 19467703.
- Bryant-Greenwood GD, Kern A, Yamamoto SY, Sadowsky DW, Novy MJ. Relaxin and the human fetal membranes. Reprod Sci. 2007 Dec;14(8 Suppl):42-5. doi: 10.1177/1933719107310821. PMID: 18089609.
- Weiss G, Goldsmith LT. Mechanisms of relaxin-mediated premature birth. Ann N Y Acad Sci. 2005 May;1041:345-50. doi: 10.1196/annals.1282.055. PMID: 15956732.
腰痛・骨盤痛
- Gutke A, Lundberg M, Östgaard HC, Öberg B. Impact of postpartum lumbopelvic pain on disability, pain intensity, health-related quality of life, activity level, kinesiophobia, and depressive symptoms. Eur Spine J. 2011 Mar;20(3):440-8. doi: 10.1007/s00586-010-1487-6. Epub 2010 Jul 1. PMID: 20593205; PMCID: PMC3048223.
- Albert HB, Godskesen M, Westergaard JG. Incidence of four syndromes of pregnancy-related pelvic joint pain. Spine (Phila Pa 1976). 2002 Dec 15;27(24):2831-4. doi: 10.1097/00007632-200212150-00020. PMID: 12486356.
- Damen L, Buyruk HM, Güler-Uysal F, Lotgering FK, Snijders CJ, Stam HJ. The prognostic value of asymmetric laxity of the sacroiliac joints in pregnancy-related pelvic pain. Spine (Phila Pa 1976). 2002 Dec 15;27(24):2820-4. doi: 10.1097/00007632-200212150-00018. PMID: 12486354.
- Kogstad O, Biørnstad N. Bekkenløsning. Patogenese/etiologi/definisjon/epidemiologi [Pelvic girdle relaxation. Pathogenesis, etiology, definition, epidemiology]. Tidsskr Nor Laegeforen. 1990 Jun 30;110(17):2209-11. Norwegian. PMID: 2142835.
- Gutke A, Josefsson A, Oberg B. Pelvic girdle pain and lumbar pain in relation to postpartum depressive symptoms. Spine (Phila Pa 1976). 2007 Jun 1;32(13):1430-6. doi: 10.1097/BRS.0b013e318060a673. PMID: 17545912.
- Biering K, Nøhr EA, Olsen J, Andersen AM, Hjøllund NH, Juhl M. Pregnancy-related pelvic pain is more frequent in women with increased body mass index. Acta Obstet Gynecol Scand. 2011 Oct;90(10):1132-9. doi: 10.1111/j.1600-0412.2011.01141.x. Epub 2011 May 20. PMID: 21446932.
- Albert H, Godskesen M, Westergaard J. Prognosis in four syndromes of pregnancy-related pelvic pain. Acta Obstet Gynecol Scand. 2001 Jun;80(6):505-10. PMID: 11380285.
- Mens JM, Vleeming A, Snijders CJ, Ronchetti I, Stam HJ. Reliability and validity of hip adduction strength to measure disease severity in posterior pelvic pain since pregnancy. Spine (Phila Pa 1976). 2002 Aug 1;27(15):1674-9. doi: 10.1097/00007632-200208010-00017. PMID: 12163732.
- Mens JMA, Pool-Goudzwaard A. The transverse abdominal muscle is excessively active during active straight leg raising in pregnancy-related posterior pelvic girdle pain: an observational study. BMC Musculoskelet Disord. 2017 Aug 25;18(1):372. doi: 10.1186/s12891-017-1732-9. PMID: 28841825; PMCID: PMC5574111.
- Elden H, Gutke A, Kjellby-Wendt G, Fagevik-Olsen M, Ostgaard HC. Predictors and consequences of long-term pregnancy-related pelvic girdle pain: a longitudinal follow-up study. BMC Musculoskelet Disord. 2016 Jul 12;17:276. doi: 10.1186/s12891-016-1154-0. PMID: 27406174; PMCID: PMC4941027.
- Albert HB, Godskesen M, Korsholm L, Westergaard JG. Risk factors in developing pregnancy-related pelvic girdle pain. Acta Obstet Gynecol Scand. 2006;85(5):539-44. doi: 10.1080/00016340600578415. PMID: 16752231.
- Bjelland EK, Eskild A, Johansen R, Eberhard-Gran M. Pelvic girdle pain in pregnancy: the impact of parity. Am J Obstet Gynecol. 2010 Aug;203(2):146.e1-6. doi: 10.1016/j.ajog.2010.03.040. Epub 2010 May 26. PMID: 20510180.
- Mens JM, Pool-Goudzwaard A. Contraction of the transverse abdominal muscle in pelvic girdle pain is enhanced by pain provocation during the task. Musculoskelet Sci Pract. 2017 Dec;32:78-83. doi: 10.1016/j.msksp.2017.09.001. Epub 2017 Sep 6. PMID: 28898747.
- Fitzgerald CM, Bennis S, Marcotte ML, Shannon MB, Iqbal S, Adams WH. The impact of a sacroiliac joint belt on function and pain using the active straight leg raise in pregnancy-related pelvic girdle pain. PM R. 2022 Jan;14(1):19-29. doi: 10.1002/pmrj.12591. Epub 2021 May 20. PMID: 33745213.
- 松岡あやか, and マツオカアヤカ. "妊産褥婦における骨盤支持の目的と方法および効用に関する文献検討." 南九州看護研究誌 12.1 (2014): 41-49.
- 田代俊之, et al. "妊婦の腰痛." 日本腰痛研究会雑誌 2.1 (1996): 22-26.
- Kordi R, Abolhasani M, Rostami M, Hantoushzadeh S, Mansournia MA, Vasheghani-Farahani F. Comparison between the effect of lumbopelvic belt and home based pelvic stabilizing exercise on pregnant women with pelvic girdle pain; a randomized controlled trial. J Back Musculoskelet Rehabil. 2013;26(2):133-9. doi: 10.3233/BMR-2012-00357. PMID: 23640314.
- Robinson HS, Eskild A, Heiberg E, Eberhard-Gran M. Pelvic girdle pain in pregnancy: the impact on function. Acta Obstet Gynecol Scand. 2006;85(2):160-4. doi: 10.1080/00016340500410024. PMID: 16532908.
- Hemmerich A, Bandrowska T, Dumas GA. The effects of squatting while pregnant on pelvic dimensions: A computational simulation to understand childbirth. J Biomech. 2019 Apr 18;87:64-74. doi: 10.1016/j.jbiomech.2019.02.017. Epub 2019 Feb 27. PMID: 30851977.
- Owe KM, Bjelland EK, Stuge B, Orsini N, Eberhard-Gran M, Vangen S. Exercise level before pregnancy and engaging in high-impact sports reduce the risk of pelvic girdle pain: a population-based cohort study of 39 184 women. Br J Sports Med. 2016 Jul;50(13):817-22. doi: 10.1136/bjsports-2015-094921. Epub 2015 Oct 4. PMID: 26435533.
- Albert HB, Godskesen M, Korsholm L, Westergaard JG. Risk factors in developing pregnancy-related pelvic girdle pain. Acta Obstet Gynecol Scand. 2006;85(5):539-44. doi: 10.1080/00016340600578415. PMID: 16752231.
- Bjelland EK, Owe KM, Stuge B, Vangen S, Eberhard-Gran M. Breastfeeding and pelvic girdle pain: a follow-up study of 10,603 women 18 months after delivery. BJOG. 2015 Dec;122(13):1765-71. doi: 10.1111/1471-0528.13118. Epub 2014 Oct 20. PMID: 25327939.
- Bjelland EK, Eberhard-Gran M, Nielsen CS, Eskild A. Age at menarche and pelvic girdle syndrome in pregnancy: a population study of 74 973 women. BJOG. 2011 Dec;118(13):1646-52. doi: 10.1111/j.1471-0528.2011.03099.x. Epub 2011 Sep 6. PMID: 21895953.
- Mens JM, Pool-Goudzwaard A, Stam HJ. Mobility of the pelvic joints in pregnancy-related lumbopelvic pain: a systematic review. Obstet Gynecol Surv. 2009 Mar;64(3):200-8. doi: 10.1097/OGX.0b013e3181950f1b. PMID: 19228440.
- Morino S, Ishihara M, Umezaki F, Hatanaka H, Yamashita M, Kawabe R, Aoyama T. The effects of pelvic belt use on pelvic alignment during and after pregnancy: a prospective longitudinal cohort study. BMC Pregnancy Childbirth. 2019 Aug 22;19(1):305. doi: 10.1186/s12884-019-2457-6. PMID: 31438891; PMCID: PMC6704663.
- 笠野由布子, and 増田一太. "女性の骨盤形態の特徴と出産経験による比較." 理学療法学 Supplement Vol. 46 Suppl. No. 1 (第 53 回日本理学療法学術大会 抄録集). 日本理学療法士協会 (現 一般社団法人日本理学療法学会連合), 2019.
子宮円靭帯痛
- Twidale, Emily Katherine, et al. "Unexplained abdominal pain in pregnancy and the use of the term ‘Round Ligament Pain’: a single-centre New Zealand pilot cohort study." (2022).
早産
- Kacerovsky M, Romero R, Stepan M, Stranik J, Maly J, Pliskova L, Bolehovska R, Palicka V, Zemlickova H, Hornychova H, Spacek J, Jacobsson B, Pacora P, Musilova I. Antibiotic administration reduces the rate of intraamniotic inflammation in preterm prelabor rupture of the membranes. Am J Obstet Gynecol. 2020 Jul;223(1):114.e1-114.e20. doi: 10.1016/j.ajog.2020.01.043. PMID: 32591087; PMCID: PMC9125527.
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羊水
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胎動
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子宮の収縮
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貧血
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膣洗浄
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腹直筋離開
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